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World journal of gastroenterology : WJG, 2009-12, Vol.15 (45), p.5722-5726
2009
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Autor(en) / Beteiligte
Titel
Gastric dysplasia may be an independent risk factor of an advanced colorectal neoplasm
Ist Teil von
  • World journal of gastroenterology : WJG, 2009-12, Vol.15 (45), p.5722-5726
Ort / Verlag
United States: The WJG Press and Baishideng
Erscheinungsjahr
2009
Quelle
Elektronische Zeitschriftenbibliothek (Open access)
Beschreibungen/Notizen
  • AIM: To evaluate the relationship between gastric dysplasia and Helicobacter pylori (H pylori) and the occurrence of colorectal adenoma, and to define the necessity for colonoscopy in patients with gastric dysplasia or Hpylori infection. METHODS: From May 2005 to February 2008, 133 patients with established gastric dysplasia by gastroduo-denoscopy (EGD) were additionally investigated by colonoscopy. The authors compared results with those of 213 subjects who underwent both EGD and colonoscopy during the same period at the author's Health Promotion Center as a control group. H pylori infection was evaluated in both the gastric dysplasia and control groups. RESULTS: The mean age of all 346 study subjects was 54.1 ± 10.5 years, and there were 258 (73%) men and 87 (27%) women. No significant difference was found between the H pylori positive and negative subjects in terms of the prevalence of colorectal adenoma and advanced colorectal adenoma (P = 0.261). Patients with gastric dysplasia showed no elevated risk of colorectal adenoma (OR = 0.910, 95% CI: 0.587-1.411, P = 0.738), but had a significantly higher risk of having advanced colorectal adenoma (OR = 3.382, 95% CI: 1.700-6.342, P = 0.000).CONCLUSION: The study emphasizes the need for colon surveillance in patients with gastric dysplasia, regardless of Hpylori infection.
Sprache
Englisch
Identifikatoren
ISSN: 1007-9327
eISSN: 2219-2840
DOI: 10.3748/wjg.15.5722
Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2789227

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