Details

Autor(en) / Beteiligte

• Polpitiya, Ashoka D.
• Qian, Wei-Jun
• Jaitly, Navdeep
• Petyuk, Vladislav A.
• Adkins, Joshua N.
• Camp, David G.
• Anderson, Gordon A.
• Smith, Richard D.

Titel

DAnTE: a statistical tool for quantitative analysis of -omics data

Ist Teil von

• Bioinformatics, 2008-07, Vol.24 (13), p.1556-1558

Ort / Verlag

Oxford: Oxford University Press

Erscheinungsjahr

2008

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Data Analysis Tool Extension (DAnTE) is a statistical tool designed to address challenges associated with quantitative bottom-up, shotgun proteomics data. This tool has also been demonstrated for microarray data and can easily be extended to other high-throughput data types. DAnTE features selected normalization methods, missing value imputation algorithms, peptide-to-protein rollup methods, an extensive array of plotting functions and a comprehensive hypothesis-testing scheme that can handle unbalanced data and random effects. The graphical user interface (GUI) is designed to be very intuitive and user friendly. Availability: DAnTE may be downloaded free of charge at http://omics.pnl.gov/software/ Contact: rds@pnl.gov or proteomics@pnl.gov Supplementary information: An example dataset with instructions on how to perform a series of analysis steps is available at http://omics.pnl.gov/software/