Details

Autor(en) / Beteiligte

• Xie, J.T
• Wang, C.Z
• Ni, M
• Wu, J.A
• Mehendale, S.R
• Aung, H.H
• Foo, A
• Yuan, C.S

Titel

American Ginseng Berry Juice Intake Reduces Blood Glucose and Body Weight in ob/ob Mice

Ist Teil von

• Journal of food science, 2007-10, Vol.72 (8), p.S590-S594

Ort / Verlag

Malden, USA: Blackwell Publishing Inc

Erscheinungsjahr

2007

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Diabetes is a serious chronic metabolic disease and has a significant impact on patients' lives and the health care system. We previously observed that the organic solvent extract of American ginseng berry possessed significant antidiabetic effects in obese diabetic ob/ob mice after intraperitoneal injection. If American ginseng berry is useful as a dietary supplement, simple preparation and oral intake would be a convenient, safe, and practical means for consumers. In this study, the simply prepared berry juice was first analyzed using high-performance liquid chromatography, and then administered orally in the ob/ob mice. The animals received daily berry juice 0.6 mL/kg or vehicle for 10 consecutive days. The results indicated that oral juice administration significantly lowered fasting blood glucose levels, and this effect continued for at least 10 d after cessation of the treatment. Data from intraperitoneal glucose tolerance test demonstrated that there was a notable improvement in glucose tolerance in the juice treated group. In addition, the berry juice significantly reduced body weight. Our data suggest that ginseng berry juice, as a dietary supplement, may have functional efficacy in consumers with diabetes.