Details

Autor(en) / Beteiligte

• Gad, S
• Lefèvre, S H
• Khoo, S K
• Giraud, S
• Vieillefond, A
• Vasiliu, V
• Ferlicot, S
• Molinié, V
• Denoux, Y
• Thiounn, N
• Chrétien, Y
• Méjean, A
• Zerbib, M
• Benoît, G
• Hervé, J M
• Allègre, G
• Bressac-de Paillerets, B
• Teh, B T
• Richard, S

Titel

Mutations in BHD and TP53 genes, but not in HNF1β gene, in a large series of sporadic chromophobe renal cell carcinoma

Ist Teil von

• British journal of cancer, 2007-01, Vol.96 (2), p.336-340

Ort / Verlag

Nature Publishing Group

Erscheinungsjahr

2007

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• BHD , TP53 , and HNF1β on chromosome 17 were studied in 92 cases of renal cell carcinoma (46 chromophobe, 19 clear cell, 18 oncocytoma, and nine papillary). Six, thirteen, and zero cases had, respectively BHD , TP53 , and HNF1β mutations, (84% mutations involved chromophobe), suggesting a role for BHD and TP53 in chromophobe subtype.