Details

Autor(en) / Beteiligte

• Moore, David A.J
• Evans, Carlton A.W
• Gilman, Robert H
• Caviedes, Luz
• Coronel, Jorge
• Vivar, Aldo
• Sanchez, Eduardo
• Piñedo, Yvette
• Saravia, Juan Carlos
• Salazar, Cayo
• Oberhelman, Richard
• Hollm-Delgado, Maria-Graciela
• LaChira, Doris
• Escombe, A. Roderick
• Friedland, Jon S

Titel

Microscopic-Observation Drug-Susceptibility Assay for the Diagnosis of TB

Ist Teil von

• The New England journal of medicine, 2006-10, Vol.355 (15), p.1539-1550

Ort / Verlag

Boston, MA: Massachusetts Medical Society

Erscheinungsjahr

2006

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• For culture and antimicrobial-susceptibility testing of Mycobacterium tuberculosis, results are typically available in 1 to 2 months. This report from Peru demonstrates that the microscopic-observation drug-susceptibility assay may be more sensitive for the detection of M. tuberculosis than the current standard techniques and that results are available in significantly less time (median, 7 days). This report from Peru demonstrates that the microscopic-observation drug-susceptibility assay may be more sensitive for the detection of M. tuberculosis than the current standard techniques and that results are available in significantly less time. Every year, 1.7 million people die of tuberculosis, a curable disease. 1 The poor are disproportionately affected, and tuberculosis further impoverishes individual people and societies. Goal 6 of the Millennium Development Goals of the United Nations includes the halting and reversal of the rising incidence of tuberculosis, and the Stop TB Partnership aims to halve the prevalence of tuberculosis and resulting deaths by 2015. 2 Existing control strategies miss important opportunities to interrupt transmission. Improved tuberculosis detection and early identification of multidrug-resistant tuberculosis are key gaps. Sputum-smear–based diagnosis under the Direct Observation of Therapy (Short Course) (DOTS) strategy of the World Health . . .