Details

Autor(en) / Beteiligte

• DIMAGNO, E P

Titel

A perspective on the use of tubeless pancreatic function tests in diagnosis

Ist Teil von

• Gut, 1998-07, Vol.43 (1), p.2-3

Ort / Verlag

London: BMJ Publishing Group Ltd and British Society of Gastroenterology

Erscheinungsjahr

1998

Quelle

MEDLINE

Beschreibungen/Notizen

• [...]with PLT and many other tubeless tests false positive results occur in patients who have a gastrectomy, hepatobiliary disease or a mucosal small bowel disease such as coeliac disease and inflammatory bowel disease. [...]non-invasive tests are not useful in this latter group of patients who are most difficult to diagnose. [...]at present the only uses for non-invasive tests are to use them in a general medical or surgical practice to screen for pancreatic insufficiency (because of their high positive predictive value in some studies) or to assess the efficacy of pancreatic enzyme replacement in patients with known severe exocrine insufficiency who are being treated with exogenous enzymes. 7 13 15 However, in the former case even if a test is abnormal, the high false positive rate in non-pancreatic malabsorption reduces the usefulness and an invasive pancreatic function test may be needed if a non-pancreatic explanation for malabsorption is not found or if the non-invasive test is normal and there is a persistent suspicion of pancreatic disease.