Genes & development, 2006-11, Vol.20 (22), p.3084-3088
2006
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- Autor(en) / Beteiligte
- Titel
- MtHAP2-1 is a key transcriptional regulator of symbiotic nodule development regulated by microRNA169 in Medicago truncatula
- Ist Teil von
- Genes & development, 2006-11, Vol.20 (22), p.3084-3088
- Ort / Verlag
- United States: Cold Spring Harbor Laboratory Press
- Erscheinungsjahr
- 2006
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- In the model legume Medicago truncatula, we identified a new transcription factor of the CCAAT-binding family, MtHAP2-1, for which RNA interference (RNAi) and in situ hybridization experiments indicate a key role during nodule development, possibly by controlling nodule meristem function. We could also show that MtHAP2-1 is regulated by microRNA169, whose overexpression leads to the same nodule developmental block as MtHAP2-1 RNAi constructs. The complementary expression pattern of miR169 and MtHAP2-1 and the phenotype of miR169-resistant MtHAP2-1 nodules strongly suggest, in addition, that the miR169-mediated restriction of MtHAP2-1 expression to the nodule meristematic zone is essential for the differentiation of nodule cells.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0890-9369eISSN: 1549-5477DOI: 10.1101/gad.402806Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1635144
- Format
- –
- Schlagworte
- Base Sequence, Gene Expression Regulation, Plant, Life Sciences, Medicago truncatula, Medicago truncatula - growth & development, Meristem - cytology, Meristem - ultrastructure, MicroRNAs - genetics, MicroRNAs - metabolism, Molecular Sequence Data, Phenotype, Plant Proteins - genetics, Plant Proteins - metabolism, Research Communication, RNA Interference, RNA Precursors - metabolism, RNA, Messenger - genetics, RNA, Messenger - metabolism, Root Nodules, Plant - cytology, Root Nodules, Plant - growth & development, Symbiosis, Transcription, Genetic, Vegetal Biology