Journal of Clinical Microbiology, 2006-05, Vol.44 (5), p.1844-1846
2006
Details
- Autor(en) / Beteiligte
- Titel
- Cytolethal Distending Toxin in Escherichia coli O157:H7: Spectrum of Conservation, Structure, and Endothelial Toxicity
- Ist Teil von
- Journal of Clinical Microbiology, 2006-05, Vol.44 (5), p.1844-1846
- Ort / Verlag
- Washington, DC: American Society for Microbiology
- Erscheinungsjahr
- 2006
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- We identified the cytolethal distending toxin V (CDT-V) gene cluster in 19 (4.9%) of 391 enterohemorrhagic Escherichia coli O157:H7. cdt-V⁺ strains belonged to five phage types (PTs) and were most frequent within PTs 14 and 34. CDT-V was expressed in all but two cdt-V⁺ strains and was lethal to cultured endothelial cells. Subtyping schemes should include cdt-V as a marker to differentiate E. coli O157:H7 even within the same phage type.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0095-1137eISSN: 1098-660X, 1098-5530DOI: 10.1128/JCM.44.5.1844-1846.2006Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1479162
- Format
- –
- Schlagworte
- Alleles, Bacterial Toxins - chemistry, Bacterial Toxins - genetics, Bacterial Toxins - toxicity, Bacteriology, Base Sequence, Biological and medical sciences, Cell Line, Conserved Sequence, Diarrhea - microbiology, DNA, Bacterial - genetics, Endothelium, Vascular - drug effects, Escherichia coli, Escherichia coli Infections - microbiology, Escherichia coli O157 - chemistry, Escherichia coli O157 - genetics, Escherichia coli O157 - pathogenicity, Evolution, Molecular, Fundamental and applied biological sciences. Psychology, Genes, Bacterial, Hemolytic-Uremic Syndrome - microbiology, Humans, Infectious diseases, Medical sciences, Microbiology, Miscellaneous, Multigene Family, Virulence - genetics