Cellular and molecular life sciences : CMLS, 2000-04, Vol.57 (4), p.542-551
2000
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- Autor(en) / Beteiligte
- Titel
- Molecular mimicry: a critical look at exemplary instances in human diseases
- Ist Teil von
- Cellular and molecular life sciences : CMLS, 2000-04, Vol.57 (4), p.542-551
- Ort / Verlag
- Switzerland: Springer Nature B.V
- Erscheinungsjahr
- 2000
- Quelle
- SpringerLink
- Beschreibungen/Notizen
- Molecular mimicry, the concept that antigenic determinants of microorganisms resemble antigenic determinants of the host, is frequently cited as a plausible mechanism to account for the association of infection and autoimmune disease. Based on analogous sequences of amino acids or on cross-reactions of monoclonal antibodies, numerous examples of such mimicry have been reported. There are, however, no clear examples of a human disease caused by molecular mimicry.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1420-682XeISSN: 1420-9071DOI: 10.1007/PL00000716Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11146766
- Format
- –
- Schlagworte
- Amino acids, Animals, Antigenic determinants, Antigens, Arthritis, Rheumatoid - immunology, Autoantigens - immunology, Autoimmune diseases, Autoimmune Diseases - etiology, Autoimmune Diseases - immunology, Chagas Disease - immunology, Diabetes Mellitus, Type 1 - immunology, Epidemiology, Epitopes, T-Lymphocyte - immunology, Humans, Lyme Disease - immunology, Microorganisms, Mimicry, Molecular biology, Molecular Mimicry - immunology, Monoclonal antibodies, Multiple Sclerosis - immunology, Myocarditis - immunology, Rheumatic Fever - immunology, Spondylitis, Ankylosing - immunology