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The Enterics for Global Health (EFGH) Shigella Surveillance Study in The Gambia
Ist Teil von
Open forum infectious diseases, 2024-03, Vol.11 (Supplement_1), p.S84-S90
Ort / Verlag
US: Oxford University Press
Erscheinungsjahr
2024
Link zum Volltext
Quelle
EZB Electronic Journals Library
Beschreibungen/Notizen
Abstract
Background
The Gambia, located in West Africa, is one of 7 country sites conducting the Enterics for Global Health (EFGH) Shigella Surveillance Study to establish incidence and consequence of Shigella-associated medically attended diarrhea among children 6–35 months old.
Methods
Here we describe the study site and research experience, sociodemographic characteristics of the study catchment area, facilities of recruitment for diarrhea case surveillance, and known care-seeking behavior for diarrheal illness. We also describe The Gambia's healthcare system and financing, current vaccine schedule and Shigella vaccine adaptation, local diarrhea management guidelines and challenges, and antibiotic resistance patterns in the region.
Conclusions
The EFGH study in The Gambia will contribute to the multisite network of Shigella surveillance study and prepare the site for future vaccine trials. In addition, the data produced will inform policy makers about prevention strategies and upcoming Shigella vaccine studies among children in this setting.
This article describes The Gambia EFGH study site, research capacities, study catchment area, and recruitment facilities. This paper also highlights sociodemographic status, healthcare-seeking behaviors for diarrhea, diarrheal case management, antibiotic resistance patterns, and new vaccine adaptation in children.