Details

Autor(en) / Beteiligte

• Neofytou, Alexander Paul
• Neji, Radhouene
• Kowalik, Grzegorz Tomasz
• Mooiweer, Ronald
• Wong, James
• Fotaki, Anastasia
• Ferreira, Joana
• Evans, Carl
• Bosio, Filippo
• Mughal, Nabila
• Razavi, Reza
• Pushparajah, Kuberan
• Roujol, Sébastien

Titel

Retrospective motion correction through multi‐average k‐space data elimination (REMAKE) for free‐breathing cardiac cine imaging

Ist Teil von

• Magnetic resonance in medicine, 2023-06, Vol.89 (6), p.2242-2254

Ort / Verlag

United States: Wiley Subscription Services, Inc

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Wiley Online Library Journals Frontfile Complete

Beschreibungen/Notizen

• Purpose To develop a motion‐robust reconstruction technique for free‐breathing cine imaging with multiple averages. Method Retrospective motion correction through multiple average k‐space data elimination (REMAKE) was developed using iterative removal of k‐space segments (from individual k‐space samples) that contribute most to motion corruption while combining any remaining segments across multiple signal averages. A variant of REMAKE, termed REMAKE+, was developed to address any losses in SNR due to k‐space information removal. With REMAKE+, multiple reconstructions using different initial conditions were performed, co‐registered, and averaged. Both techniques were validated against clinical “standard” signal averaging reconstruction in a static phantom (with simulated motion) and 15 patients undergoing free‐breathing cine imaging with multiple averages. Quantitative analysis of myocardial sharpness, blood/myocardial SNR, myocardial‐blood contrast‐to‐noise ratio (CNR), as well as subjective assessment of image quality and rate of diagnostic quality images were performed. Results In phantom, motion artifacts using “standard” (RMS error [RMSE]: 2.2 ± 0.5) were substantially reduced using REMAKE/REMAKE+ (RMSE: 1.5 ± 0.4/1.0 ± 0.4, p < 0.01). In patients, REMAKE/REMAKE+ led to higher myocardial sharpness (0.79 ± 0.09/0.79 ± 0.1 vs. 0.74 ± 0.12 for “standard”, p = 0.004/0.04), higher image quality (1.8 ± 0.2/1.9 ± 0.2 vs. 1.6 ± 0.4 for “standard”, p = 0.02/0.008), and a higher rate of diagnostic quality images (99%/100% vs. 94% for “standard”). Blood/myocardial SNR for “standard” (94 ± 30/33 ± 10) was higher vs. REMAKE (80 ± 25/28 ± 8, p = 0.002/0.005) and tended to be lower vs. REMAKE+ (105 ± 33/36 ± 12, p = 0.02/0.06). Myocardial‐blood CNR for “standard” (61 ± 22) was higher vs. REMAKE (53 ± 19, p = 0.003) and lower vs. REMAKE+ (69 ± 24, p = 0.007). Conclusions Compared to “standard” signal averaging reconstruction, REMAKE and REMAKE+ provide improved myocardial sharpness, image quality, and rate of diagnostic quality images.