Details

Autor(en) / Beteiligte

• Gjorup, Caroline A.
• Woodford, Rachel
• Li, Isabel
• Carlino, Matteo S.
• Ch’ng, Sydney
• Chung, David
• Hsiao, Edward
• Lo, Serigne N.
• London, Kevin
• Long, Georgina V.
• Menzies, Alexander M.
• Nieweg, Omgo E.
• Pennington, Thomas E.
• Rtshiladze, Michael A.
• Saw, Robyn P. M.
• Scolyer, Richard A.
• Shannon, Kerwin F.
• Spillane, Andrew J.
• Stretch, Jonathan R.
• Thompson, John F.
• Varey, Alexander H. R.
• van Akkooi, Alexander C. J.

Titel

Role of Concurrent Ultrasound Surveillance of Sentinel Node-Positive Node Fields in Melanoma Patients Having Routine Cross-Sectional Imaging

Ist Teil von

• Annals of surgical oncology, 2024-03, Vol.31 (3), p.1857-1864

Ort / Verlag

Cham: Springer International Publishing

Erscheinungsjahr

2024

Quelle

MEDLINE

Beschreibungen/Notizen

• Purpose In sentinel node-positive (SN+ve) melanoma patients, active surveillance with regular ultrasound examination of the node field has become standard, rather than completion lymph node dissection (CLND). A proportion of these patients now receive adjuvant systemic therapy and have routine cross-sectional imaging (computed tomography [CT] or positron emission tomography [PET]/CT). The role of concurrent ultrasound (US) surveillance in these patients is unclear. The purpose of our study was to describe the modality of detection of nodal recurrence in SN+ve node fields. Methods SN+ve melanoma patients who did not undergo CLND treated at a single institution from January 1, 2016 to December 31, 2020 were included. Results A total of 225 SN+ve patients with a median follow-up of 23 months were included. Of these, 119 (53%) received adjuvant systemic therapy. Eighty (36%) developed a recurrence at any site; 24 (11%) recurred first in the SN+ve field, of which 12 (5%) were confirmed node field recurrence only at 2 months follow-up. The nodal recurrences were first detected by ultrasound in seven (3%), CT in seven (3%), and PET/CT in seven (3%) patients. All nodal recurrences evident on US were also evident on PET/CT and vice versa. Conclusions The high rate of recurrences outside the node field and the identification of all US-detected nodal recurrences on concurrent cross-sectional imaging modalities suggest that routine concurrent ultrasound surveillance of the node-positive field may be unnecessary for SN+ve melanoma patients having routine cross-sectional imaging.