Details

Autor(en) / Beteiligte

• Odayar, Jasantha
• Phillips, Tamsin K
• Kabanda, Siti
• Malaba, Thokozile R
• Mukonda, Elton
• Hsiao, Nei-yuan
• Lesosky, Maia
• Myer, Landon

Titel

Mobility during the post-partum period and viraemia in women living with HIV in South Africa

Ist Teil von

• International health, 2023-11, Vol.15 (6), p.692-701

Ort / Verlag

England: Oxford University Press

Erscheinungsjahr

2023

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Abstract Background We investigated the association between travel and viraemia in post-partum women with human immunodeficiency virus on antiretroviral therapy (ART). Methods Data are from a trial of post-partum ART delivery strategies. Women who initiated ART during pregnancy, were clinically stable with a viral load (VL) <400 copies/ml and were <10 weeks post-partum were enrolled at a primary care antenatal clinic in Cape Town, South Africa. Study visits at 3, 6, 12, 18 and 24 months post-partum included questions about travel, defined as ≥1 night spent outside of the city, and VL testing. Generalised mixed effects models assessed the association between travel and subsequent VL ≥400 copies/ml. Results Among 402 women (mean age 29 y, 35% born in the Western Cape), 69% reported one or more travel events over 24 months. Being born beyond the Western Cape (adjusted odds ratio [aOR] 2.03 [95% confidence interval {CI} 1.49 to 2.77]), duration post-partum in months (aOR 1.03 [95% CI 1.02 to 1.05]) and living with the child (aOR 0.60 [95% CI 0.38 to 0.93]) were associated with travel. In multivariable analyses, a travel event was associated with a 92% increase in the odds of a VL ≥400 copies/ml (aOR 1.92 [95% CI 1.19 to 3.10]). Conclusions Interventions to support women on ART who travel are urgently required.