Details

Autor(en) / Beteiligte

• Gunaseelan, Indusaa
• Amin Zadeh, Alaleh
• Arhatari, Benedicta
• Maksimenko, Anton
• Hall, Christopher
• Hausermann, Daniel
• Kumar, Beena
• Fox, Jane
• Quiney, Harry
• Lockie, Darren
• Lewis, Sarah
• Brennan, Patrick
• Gureyev, Timur
• Tavakoli Taba, Seyedamir

Titel

Propagation-based phase-contrast imaging of the breast: image quality and the effect of X-ray energy and radiation dose

Ist Teil von

• British journal of radiology, 2023-10, Vol.96 (1150), p.20221189-20221189

Ort / Verlag

The British Institute of Radiology

Erscheinungsjahr

2023

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Objectives: Propagation-based phase-contrast computed tomography (PB-CT) is a new imaging technique that exploits refractive and absorption properties of X-rays to enhance soft tissue contrast and improve image quality. This study compares image quality of PB-CT and absorption-based CT (AB-CT) for breast imaging while exploring X-ray energy and radiation dose. Methods: Thirty-nine mastectomy samples were scanned at energy levels of 28-34keV using a flat panel detector at radiation dose levels of 4mGy and 2mGy. Image quality was assessed using signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), spatial resolution (res) and visibility (vis). Statistical analysis was performed to compare PB-CT images against their corresponding AB-CT images scanned at 32keV and 4mGy. Results: The PB-CT images at 4mGy, across nearly all energy levels, demonstrated superior image quality than AB-CT images at the same dose. At some energy levels, the 2mGy PB-CT images also showed better image quality in terms of CNR/Res and vis compared to the 4mGy AB-CT images. At both investigated doses, SNR and SNR/res were found to have a statistically significant difference across all energy levels. The difference in vis was statistically significant at some energy levels. Conclusion: This study demonstrates superior image quality of PB-CT over AB-CT, with X-ray energy playing a crucial role in determining image quality parameters. Advances in knowledge: Our findings reveal that standard dose PB-CT outperforms standard dose AB-CT across all image quality metrics. Additionally, we demonstrate that low dose PB-CT can produce superior images compared to standard dose AB-CT in terms of CNR/Res and vis.