Details

Autor(en) / Beteiligte

• Campagnari, Simone
• Casari, Rebecca
• Zamboni, Lorenzo
• Fusina, Francesca
• Lugoboni, Fabio

Titel

Cytisine induced urticaria: a case report during a smoking cessation treatment

Ist Teil von

• Acta bio-medica de l'Ateneo Parmense, 2022-06, Vol.93 (Suppl 1)

Ort / Verlag

Italy: Mattioli 1885

Erscheinungsjahr

2022

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Cytisine is considered to be the oldest medication for smoking cessation and has been used for this purpose in some Eastern/Central European and Central Asian countries for over 50 years 1 , 2 . Like Varenicline, it is a partial agonist of the nicotinic acetylchloline receptors (nAChRs) with high affinity for the alpha-4 beta-2 nAChRs subtype, and its main action is to reduce withdrawal symptoms following smoking cessation 3 , 4 . Several sources points towards cytisine’s efficacy and effectiveness; it’s well tolerated when taken at the recommended dose, and adverse events reported in trials are typically non-serious and self-limiting gastrointestinal and sleep disturbances 5 – 7 . We report the first observed case of cytisine hypersensitivity reaction during a smoking cessation treatment. ( www.actabiomedica.it )