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Weight Loss With Rising Blood Glucose: Challenges in Distinguishing Conventional Type 2 Diabetes From Pancreatic Cancer-Associated Hyperglycemia
Ist Teil von
Clinical diabetes, 2023-07, Vol.41 (3), p.477-480
Ort / Verlag
United States: American Diabetes Association
Erscheinungsjahr
2023
Quelle
EZB Electronic Journals Library
Beschreibungen/Notizen
Johannes and Westcott discuss the case study of a 56-year-old female recreational cyclist who presented to her primary care provider (PCP) with postprandial hyperglycemia, new-onset upper abdominal pain worse with fatty meals, and weight loss. Because of severe hyperglycemia from glycemic excursions, worsening abdominal pain, and pruritus, the patient presented to a local emergency department, where urinalysis revealed moderate bilirubin. In follow-up with the PCP, her A1C had risen to 7%, her serum C-peptide concentration was 1.39 ng/mL, and her blood glucose was 285 mg/dL. Insulin glargine 20 units daily was initiated. A Helicobacter pylori urea breath test was negative, and upper endoscopy was recommended. Given her high postprandial blood glucose levels, insulin aspart with meals was initiated, and metformin was discontinued because of abdominal pain and loose stools.