Details

Autor(en) / Beteiligte

• Smoke, Steven M
• Brophy, Alison
• Reveron, Samuel
• Iovleva, Alina
• Kline, Ellen G
• Marano, Michael
• Miller, Lincoln P
• Shields, Ryan K

Titel

Evolution and Transmission of Cefiderocol-Resistant Acinetobacter baumannii During an Outbreak in the Burn Intensive Care Unit

Ist Teil von

• Clinical infectious diseases, 2023-02, Vol.76 (3), p.e1261-e1265

Ort / Verlag

United States: Oxford University Press

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Oxford Journals 2020 Medicine

Beschreibungen/Notizen

• We report on 11 critically ill burn patients treated with cefiderocol for carbapenem-resistant Acinetobacter baumannii infections. Clinical success was achieved in 36% and complicated by treatment-emergent resistance and interpatient transmission of cefiderocol-resistant A. baumannii. Resistant isolates harbored disrupted pirA and piuA genes that were not disrupted among susceptible isolates.