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Information capacity of the nucleotide sequences and their fragments
Ist Teil von
Biofizika, 1997-09, Vol.42 (5), p.1047
Ort / Verlag
Russia (Federation)
Erscheinungsjahr
1997
Quelle
MEDLINE
Beschreibungen/Notizen
The problem of determining the information content of nucleotide sequences is discussed. Exact expressions for the reconstitution of higher-order frequency dictionaries from lower-order once were obtained by the maximum entropy method. In form, they are analogous to superpositional approximations known in statistical physics. The features of entropy characteristics of real nucleotide sequences are described that reliably distinguish them from random texts. Methods for comparing the information content of frequency dictionaries and assessing the residual uncertainty of the text at the known frequency dictionary are proposed.