Details

Autor(en) / Beteiligte

• Sprance, H E
• Shope, R E

Titel

Single inoculation immune hamster sera for typing California group arboviruses by the complement-fixation test

Ist Teil von

• The American journal of tropical medicine and hygiene, 1977-05, Vol.26 (3), p.544-546

Ort / Verlag

United States

Erscheinungsjahr

1977

Quelle

MEDLINE

Beschreibungen/Notizen

• Eight reference California group viruses of North America were typed using sera of immune hamsters bled 21 days after a single inoculation. The complement-fixation test reactions were relatively specific, although only 2-fold differences were observed reciprocally with the closely-related La Crosse and snowshoe hare viruses. Hamster serum taken 10 days post inoculation was more specific than a 21-day serum. Sepcificity after second inoculation was lost with some antigens. Jamestown Canyon and South River viruses were identical by complement-fixation test and showed minor differences in the plaque reduction neutralization test.