Details

Autor(en) / Beteiligte

• Kurt, Thomas L.
• Morgan, Melvin L.
• Hnilica, Violet
• Bost, Robert
• Petty, Charles S.

Titel

Fatal Iatrogenic Iodine Toxicity in a Nine-Week-Old Infant

Ist Teil von

• Clinical toxicology (Philadelphia, Pa.), 1996, Vol.34 (2), p.231-234

Ort / Verlag

Monticello, NY: Informa UK Ltd

Erscheinungsjahr

1996

Quelle

Taylor & Francis Journals Auto-Holdings Collection

Beschreibungen/Notizen

• Background: Povidone-iodine has been used since the 1950s for various labelled uses as a topical antiseptic. The toxicity of an excessive dose in internal use is described in this case report. Case Report: A 9-week-old infant was treated for colic by a pediatric gastroenterologist with loperamide and the elimination of nonhuman milk. Without improvement he was hospitalized and given an enema of 50 mL of povidone-iodine diluted in 250 mL of a bowel irrigant. The enema was promptly expelled and 50 mL of the described solution was given hourly for three doses by nasogastric tube. The infant was found lifeless three hours after the last dose and resuscitation was unsuccessful. Autopsy showed a corroded and necrotic intestinal tract, serous fluid in body cavities, a blood total iodine of 14,600 ng/dL, protein-bound iodine of 3,400 μg/dL and inorganic iodine of 11,700 μg/dL.