Details

Autor(en) / Beteiligte

• Finelli, D A
• Hurst, G C
• Gullapali, R P
• Bellon, E M

Titel

Improved contrast of enhancing brain lesions on postgadolinium, T1-weighted spin-echo images with use of magnetization transfer

Ist Teil von

• Radiology, 1994-02, Vol.190 (2), p.553-559

Ort / Verlag

United States

Erscheinungsjahr

1994

Quelle

MEDLINE

Beschreibungen/Notizen

• To prove that the contrast of enhancing brain lesions on post-gadolinium T1-weighted spin-echo (SE) images can be statistically significantly improved with magnetization-transfer (MT) indirect saturation. The contrast-to-noise ratios (C/Ns) of 201 enhancing brain lesions in 110 patients were compared on conventional and MT T1-weighted SE images obtained at 1.5 T after injection of 0.05-0.10 mmol/kg gadopentetate dimeglumine or gadodiamide. The MT T1-weighted SE images showed a 37% reduction in signal intensity of background white matter and thereby provided a 108% improvement in the C/N of enhancing brain lesions over the conventional T1-weighted SE images (P < .001). The C/Ns obtained with single-dose gadolinium and the MT T1-weighted SE technique were twice those obtained with the conventional technique and are at least equivalent to reported values obtained with triple-dose gadolinium and conventional T1-weighted SE images.