Details

Autor(en) / Beteiligte

• Ditchfield, M R
• De Campo, J F
• Cook, D J
• Nolan, T M
• Powell, H R
• Sloane, R
• Grimwood, K
• Cahill, S

Titel

Vesicoureteral reflux: an accurate predictor of acute pyelonephritis in childhood urinary tract infection?

Ist Teil von

• Radiology, 1994-02, Vol.190 (2), p.413

Ort / Verlag

United States

Erscheinungsjahr

1994

Quelle

MEDLINE

Beschreibungen/Notizen

• To determine the association between vesicoureteral reflux (VUR) and the presence of acute pyelonephritis in children with urinary tract infections. The authors studied 150 consecutive patients less than 5 years of age with their first proved urinary tract infection. All patients underwent renal cortical scintigraphy (with technetium-99m dimercaptosuccinic acid or Tc-99m gluconate) and voiding cystourethrography (VCUG) to identify the presence of cortical defects and VUR, respectively. Of 300 kidneys, 88 (29.3%) had a cortical defect at scintigraphy. Fifty-four of the 88 patients (61%) did not have VUR demonstrated at VCUG. Conversely, 72 of the 300 kidneys (24%) had VUR; of these, 38 (53%) had no cortical defect. The sensitivity of VCUG in helping predict a defect was 38.6%, and the specificity was 82.1%. VUR (as shown by VCUG) and renal cortical scintigraphic defects frequently occur independently of each other. Renal cortical scintigraphy may be a more accurate predictor of patients at risk for scarring.