Details

Autor(en) / Beteiligte

• Zagni, R
• Cortelazzi, R
• Cipolla, L
• Giannetta, G
• Ferrante, B
• Soliani, A

Titel

Therapy of simple endometrial hyperplasia with GnRH analogs. Evaluation of a multicentric ambulatory study. Preliminary results

Ist Teil von

• Minerva ginecologica, 1993-12, Vol.45 (12), p.597

Ort / Verlag

Italy

Erscheinungsjahr

1993

Quelle

MEDLINE

Beschreibungen/Notizen

• Endometrial hyperplasia is a frequent pathology during menopause and involves the risk of malignant transformation of the lesions. In an attempt to avoid radical surgery, this study proposes the use of triptorelin which was used to treat 56 patients with histologically confirmed symptoms of endometrial hyperplasia without atypia. GnRH-analog was administered using the intramuscular route every 28 days for 6 months. Histological controls were carried out 30 days after the last injection and showed the resolution of histological symptoms, confirmed after three months.