Details

Autor(en) / Beteiligte

• Sawin, P D
• Traynelis, V C
• Follett, K A

Titel

Spinal epidural hematoma following coronary thrombolysis with tissue plasminogen activator. Report of two cases

Ist Teil von

• Journal of neurosurgery, 1995-08, Vol.83 (2), p.350-353

Ort / Verlag

United States

Erscheinungsjahr

1995

Quelle

MEDLINE

Beschreibungen/Notizen

• Two cases of spinal epidural hematoma following intravenous administration of recombinant tissue-type plasminogen activator are presented. Both patients received thrombolytic therapy for acute myocardial infarction; back pain and progressive neurological dysfunction ensued, secondary to spinal cord compression caused by epidural hematoma. Both individuals underwent emergency surgery for decompression and hematoma evacuation, resulting in improvement in neurological function. The current status of thrombolytic therapy is reviewed, with emphasis on complications of therapy that require neurosurgical intervention.