Details

Autor(en) / Beteiligte

• Katsohi, D
• Krenkel, B
• Schmachtenberg, A
• Ammon, J

Titel

10 years' experiences with an innovative irradiation technic in breast carcinoma. An analysis of the late sequelae in normal tissue

Ist Teil von

• Strahlentherapie und Onkologie, 1995-11, Vol.171 (11), p.649

Ort / Verlag

Germany

Erscheinungsjahr

1995

Quelle

MEDLINE

Beschreibungen/Notizen

• In "high risk" breast cancer patients radio- and chemotherapy or hormonal strategies are applied after mastectomy. To reduce the risk of hot spots we developed an innovative irradiation technique using only 2 portals to encompass the chest wall and the regional lymph node areas. In a retrospective analysis we evaluated 131 patients concerning late normal tissue reactions. We compared one group of combined treated patients (radio- and chemotherapy) with women who only had irradiation after surgery. The most frequent findings are telangiectasia in the chest wall (electron portal): grade 3 (1.5%), grade 2 (4.6%), grade 1 (35.8%), 58% no telangiectasia. A moderate lymphoedema of the arm was seen in 4.5%. There was no statistically significant difference between the 2 groups. Our treatment concept allows simultaneous application of radio- and chemotherapy without enhancement of late normal tissue reactions.