Details

Autor(en) / Beteiligte

• Shemesh, J
• Apter, S
• Rozenman, J
• Lusky, A
• Rath, S
• Itzchak, Y
• Motro, M

Titel

Calcification of coronary arteries: detection and quantification with double-helix CT

Ist Teil von

• Radiology, 1995-12, Vol.197 (3), p.779-783

Ort / Verlag

United States

Erscheinungsjahr

1995

Quelle

MEDLINE

Beschreibungen/Notizen

• To evaluate the accuracy of double-helix computed tomography (CT) in coronary artery calcification detection and quantification. One hundred sixty patients with coronary disease (135 men, 25 women; age range, 45-62 years), of whom 138 had obstructive (stenosis of > 50% of diameter; n = 129) or mild (< 50% stenosis; n = 9) coronary artery disease (CAD) and 22 had normal coronary arteries (per angiographic findings), and 56 age-matched healthy control subjects underwent double-helix CT. Double-helix CT findings indicated that calcification was significantly more prevalent in patients with CAD (> 83%) than in patients with normal coronary arteries (27%) or in healthy control subjects (34%; P < .01). Sensitivity in detecting obstructive CAD was high (91%); however, specificity was low (52%) because of calcification in nonobstructive lesions. Comparison of double-helix CT and angiographic findings indicated that double-helix CT was 84% accurate with positive and negative predictive values of 89% and 59%, respectively. Double-helix CT is a useful noninvasive method for detection and quantification of coronary artery calcification.