Details

Autor(en) / Beteiligte

• Orlova, Ts R
• Ragimov, S E
• Shlain, V A
• Sakharov, M P
• Trubetskoĭ, A V

Titel

Effect of inotropic factors in the postload characteristics of the heart

Ist Teil von

• Biulleten' eksperimental'noi biologii i meditsiny, 1982-06, Vol.93 (6), p.5

Ort / Verlag

Russia (Federation)

Erscheinungsjahr

1982

Quelle

MEDLINE

Beschreibungen/Notizen

• It was shown in acute experiments on cats that the post-exercise characteristics of the left ventricle plotted as a dependence between the magnitudes of the maximal blood flow velocity and systolic intraventricular pressure in health and inotropic exposures are close to the linear ones. Adrenaline shifts the post-exercise characteristics upward and to the right, increasing both the maximal magnitude of the blood flow velocity at a zero pressure (velocity component) and the maximal magnitude of the pressure at a zero blood flow (force component), the latter rising to a greater extent. Calcium chloride and obsidan cause a parallel shift of the post-exercise characteristics: the force and velocity components diminish upon obsidan administration, while with CaCl2 they increase.