Details

Autor(en) / Beteiligte

• Dolezel, S
• Gerova, M
• Hartmannova, B
• Dostal, M
• Janeckova, H
• Vasku, J

Titel

Cardiac adrenergic innervation after instrumentation of the coronary artery in dog

Ist Teil von

• American journal of physiology. Heart and circulatory physiology, 1984-03, Vol.246 (3), p.H459-H465

Ort / Verlag

Bethesda, MD: American Physiological Society

Erscheinungsjahr

1984

Quelle

MEDLINE

Beschreibungen/Notizen

• S. Dolezel, M. Gerova, B. Hartmannova, M. Dostal, H. Janeckova and J. Vasku A fine methacrylate ring (not constricting the artery) was placed around the ramus interventricularis anterior (RIA) of the left coronary artery in dogs. By means of Falck's histochemical technique an extensive degeneration of the vasomotor and cardiomotor adrenergic innervation of ventricles was detected 14 days after the procedure. The innervation of atria remained intact. The surgical intervention as well as the scarring process (which compressed the conducting parts of axons composing the perivascular nerves) induced the degeneration. The results have important implications for experiments with instrumented arteries.