Details

Autor(en) / Beteiligte

• Pavillard, E R
• Miles, H

Titel

A study of cefoperazone alone and in combination with tobramycin against Pseudomonas aeruginosa

Ist Teil von

• Clinical therapeutics, 1980, Vol.3 (Spec Issue), p.134

Ort / Verlag

United States

Erscheinungsjahr

1980

Quelle

MEDLINE

Beschreibungen/Notizen

• The minimum inhibitory concentrations (MICs) of cefoperazone for 507 clinical isolates of Pseudomonas aeruginosa were measured by plate dilution technique. On a cumulative percentage basis, 81% of isolates were inhibited by less than or equal 3.13 microgram/ml of cefoperazone. The minimum bactericidal concentration (MBC) was found to be generally twice the MIC. Synergy occurred between cefoperazone and tobramycin, judged by a lowering of the MIC in 69% of isolates, for which the MIC of cefoperazone alone was less than or equal to 6.2 microgram/ml.