Details

Autor(en) / Beteiligte

• Sautter, R D
• Koch, E L
• Myers, W O
• Ray, 3rd, J R
• Mazza, J J
• Larson, D E
• Chen, H M
• Milbauer, J P
• Treuhaft, P S
• Plotka, E D

Titel

Aspirin-sulfinpyrazone in prophylaxis of deep venous thrombosis in total hip replacement

Ist Teil von

• JAMA : the journal of the American Medical Association, 1983-11, Vol.250 (19), p.2649

Ort / Verlag

United States

Erscheinungsjahr

1983

Quelle

MEDLINE

Beschreibungen/Notizen

• In postoperative hip arthroplasty patients, treatment with aspirin and sulfinpyrazone resulted in a statistically significant reduction of venographically diagnosed thrombi in the proximal veins of the leg. This reduction was most apparent in thrombi that involved the iliac vein. When compared with their placebo-treated counterparts, female patients who received the active treatment experienced a statistically significant 75% reduction of thrombosis, compared with a 32% reduction for men that was not statistically significant. There were no serious adverse effects. Factors were identified that may influence the result of drug prophylaxis trials in deep-vein thrombosis.