Details

Autor(en) / Beteiligte

• Doroshenko, N V
• Alekseeva, I L
• Zairov, G K
• Shakhgil'dian, I V
• Konstantinova, L A

Titel

Determination of hepatitis A virus in the feces of patients in the dynamics of the infectious process

Ist Teil von

• Voprosy virusologiĭ, 1982-05, Vol.27 (3), p.308

Ort / Verlag

Russia (Federation)

Erscheinungsjahr

1982

Quelle

MEDLINE

Beschreibungen/Notizen

• Excretion of hepatitis A virus (HAV) in the time course of the infectious process is described. Among 197 fecal specimens collected from 45 patients HAV was found in 40 (20.5%); in 51% of the patients the virus was isolated in the 1st week of the icteric period, in 25% in the 2nd week and in 4% in the 3rd week. The buoyant density in cesium chloride gradient of virus specimens obtained on the 1st-2nd day of jaundice was represented by one peak of 1.30-1.35 g/cm3, whereas the material collected at late periods of the disease had heterogeneous buoyant density in zones from 1.24 to 1.43 g/cm3. The immune electron microscopic studies showed the fecal specimens collected early in the disease to be richer in virus than those collected at later intervals.