Details

Autor(en) / Beteiligte

• Power, K G
• Jerrom, D W
• Simpson, R J
• Mitchell, M

Titel

Controlled study of withdrawal symptoms and rebound anxiety after six week course of diazepam for generalised anxiety

Ist Teil von

• British medical journal (Clinical research ed.), 1985-04, Vol.290 (6477), p.1246

Ort / Verlag

England

Erscheinungsjahr

1985

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• A group of patients suffering from anxiety, as assessed by general practitioners and psychologists using research criteria for generalised anxiety, were treated with either diazepam or placebo double blind for six weeks. This active treatment period was preceded by a one week single blind placebo "wash in" period and followed by a two week single blind placebo "wash out" period. The results suggest that diazepam can produce rebound anxiety and withdrawal symptoms when used in moderate doses and for what has previously been regarded as a safe length of time. If replicated these results have implications for the therapeutic use of benzodiazepines.