Details

Autor(en) / Beteiligte

• Belančić, Andrej
• Hlača, Nika
• Peternel, Sandra
• Golčić, Marin
• Prpić‐Massari, Larisa
• Vlahović‐Palčevski, Vera

Titel

Afatinib‐induced toxic epidermal necrolysis: A case report with a literature review

Ist Teil von

• British journal of clinical pharmacology, 2024-08, Vol.90 (8), p.2030-2033

Ort / Verlag

England

Erscheinungsjahr

2024

Quelle

Wiley Online Library

Beschreibungen/Notizen

• We present a 70‐year‐old female patient diagnosed with epidermal growth factor receptor‐mutated metastatic non‐small cell lung cancer (T4N2M1a), who developed afatinib‐induced toxic epidermal necrolysis (TEN). We have also performed a PubMed/Medline literature review to detect other possible cases of TEN/Stevens–Johnson syndrome associated with afatinib treatment and found only 5 other cases reported. To our best knowledge, this is the first case of afatinib‐induced TEN successfully treated with cyclosporine.