Details

Autor(en) / Beteiligte

• Hellmuth, Johannes C
• Koch, Raphael
• Weigert, Oliver

Titel

Targeted therapies in the management of malignant lymphoma - is the end of conventional chemotherapy near?

Ist Teil von

• Deutsche medizinische Wochenschrift (1946), 2024-05, Vol.149 (11), p.621

Ort / Verlag

Germany

Erscheinungsjahr

2024

Quelle

MEDLINE

Beschreibungen/Notizen

• Advances in the understanding of the biology of malignant lymphoma has facilitated the development of numerous molecularly targeted therapies. The incorporation of these precision therapeutics has produced more effective and often less-toxic treatment regimens leading to a significant improvement of treatment outcomes for individuals with lymphoid malignancies.In relapsed diseases, molecularly targeted therapeutic approaches have demonstrated superior outcomes compared to conventional chemotherapy, leading to a growing number of patients being treated entirely chemotherapy-free. This review outlines the current landscape of targeted therapies for both B-cell (B-NHL) and T-cell non-Hodgkin lymphomas (T-NHL) and provides an overview of targeted agents currently approved for the treatment of malignant lymphoma.