Details

Autor(en) / Beteiligte

• Ito, Hisaaki
• Honma, Taro
• Tabata, Hidetsugu
• Koyama, Tomoyuki
• Ueno, Shigeaki
• Kita, Kayoko
• Suzuki, Toshihide

Titel

Enzyme from Padina arborescens Holmes Synthesizes Parinaric Acid, a Conjugated Tetraenoic Fatty Acid, from α-Linolenic Acid

Ist Teil von

• Journal of Oleo Science, 2024, Vol.73(5), pp.743-749

Ort / Verlag

Japan: Japan Oil Chemists' Society

Erscheinungsjahr

2024

Quelle

MEDLINE

Beschreibungen/Notizen

• Conjugated fatty acids have anticancer effects. Therefore, the establishment of a synthetic method for conjugated fatty acids is important for overcoming cancer. Here, we attempted to synthesize conjugated fatty acids using enzymes extracted from seaweeds containing these fatty acids. Lipids from 12 species of seaweeds from the seas around Japan were analyzed, and Padina arborescens Holmes was found to contain conjugated fatty acids. Then, we synthesized parinaric acid, a conjugated tetraenoic acid, from α-linolenic acid using the enzyme of P. arborescens. This method is expected to have a variety of potential applications for overcoming cancer.