Details

Autor(en) / Beteiligte

• Storch, H H
• Saggau, W
• Graf, K
• Ulmer, H
• Schmitz, W

Titel

Indications for ligation of ductus arteriosus Botalli persistens in premature infants

Ist Teil von

• Langenbecks Archiv für Chirurgie, 1986, Vol.369, p.355

Ort / Verlag

Germany

Erscheinungsjahr

1986

Quelle

MEDLINE

Beschreibungen/Notizen

• Ligation of patent ductus arteriosus can be safely performed even in the smallest prematures and may be life-saving. Medical treatment with prostaglandin-inhibitors may be substituted in selected cases. From 1976-1985 a total of 215 prematures was treated. 52 of those experienced spontaneous closure. In 68 infants closure occurred following indomethacin-treatment. 48 had operation after failure of medical therapy and 53 with contraindications to indomethacin were primarily operated. The overall mortality reached 20% and was highest among those with combined medical and surgical treatment.