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Indications for ligation of ductus arteriosus Botalli persistens in premature infants
Ist Teil von
Langenbecks Archiv für Chirurgie, 1986, Vol.369, p.355
Ort / Verlag
Germany
Erscheinungsjahr
1986
Quelle
MEDLINE
Beschreibungen/Notizen
Ligation of patent ductus arteriosus can be safely performed even in the smallest prematures and may be life-saving. Medical treatment with prostaglandin-inhibitors may be substituted in selected cases. From 1976-1985 a total of 215 prematures was treated. 52 of those experienced spontaneous closure. In 68 infants closure occurred following indomethacin-treatment. 48 had operation after failure of medical therapy and 53 with contraindications to indomethacin were primarily operated. The overall mortality reached 20% and was highest among those with combined medical and surgical treatment.