Details

Autor(en) / Beteiligte

• Peng, Q
• Wu, N
• Huang, Y
• Zhao, S J
• Tang, W
• Liang, M
• Ran, Y L
• Xiao, T
• Yang, L
• Liang, X

Titel

Diagnostic values of conventional tumor markers and their combination with chest CT for patients with stageⅠA lung cancer

Ist Teil von

• Zhōnghuá zhŏngliú zázhì, 2023-11, Vol.45 (11), p.934

Ort / Verlag

China

Erscheinungsjahr

2023

Quelle

MEDLINE

Beschreibungen/Notizen

• To investigate the diagnostic efficiency of conventional serum tumor markers and their combination with chest CT for stage ⅠA lung cancer. A total of 1 155 patients with stage ⅠA lung cancer and 200 patients with benign lung lesions (confirmed by surgery) treated at the Cancer Hospital, Chinese Academy of Medical Sciences from January 2016 to October 2020 were retrospectively enrolled in this study. Six conventional serum tumor markers [carcinoembryonic antigen (CEA), carbohydrate antigen 125 (CA125), squamous cell carcinoma associated antigen (SCCA), cytokeratin 19 fragment (CYFRA21-1), neuron-specific enolase (NSE), and gastrin-releasing peptide precursor (ProGRP)] and chest thin-slice CT were performed on all patients one month before surgery. Pathology was taken as the gold standard to analyze the difference of positivity rates of tumor markers between the lung cancer group and the benign group, the moderate/poor differentiation group and the well differentiation group, the adenocarcinoma group and the sq