Details

Autor(en) / Beteiligte

• Ani, Fares
• Ayres, Ethan W.
• Soroceanu, Alex
• Mundis, Gregory M.
• Smith, Justin S.
• Gum, Jeffrey L.
• Daniels, Alan H.
• Klineberg, Eric O.
• Ames, Christopher P.
• Bess, Shay
• Shaffrey, Christopher I.
• Schwab, Frank J.
• Lafage, Virginie
• Protopsaltis, Themistocles S.

Titel

Functional Alignment Within the Fusion in Adult Spinal Deformity (ASD) Improves Outcomes and Minimizes Mechanical Failures

Ist Teil von

• Spine (Philadelphia, Pa. 1976), 2024-03

Erscheinungsjahr

2024

Beschreibungen/Notizen

• Study Design. Retrospective review of an adult deformity database. Objective. To identify Pelvic Incidence (PI) and age-appropriate physical function alignment targets using a component angle of T1- Pelvic Angle (TPA) within the fusion to define correction and their relationship to proximal junctional kyphosis (PJK) and clinical outcomes. Summary of Background Data. In preoperative planning, a patient’s PI is often utilized to determine alignment target. In a trend toward more patient specific planning, age-specific alignment has been shown to reduce the risk of mechanical failures. PI and age have not been analyzed with respect to defining a functional alignment. Methods. A database of patients with operative adult spinal deformity (ASD) was analyzed. Patients fused to the pelvis and upper-instrumented vertebrae (UIV) above T11 were included. Alignment within the fusion correlated with clinical outcomes and PI. Short form 36-physical Component score (SF36-PCS) normative data and PI were used to compute functional alignment for each patient. Over-, under-, and functionally corrected groups were determined using T10-pelvic angle (T10PA). Results. 1052 patients met inclusion criteria. T10PA correlated with SF36-PCS and PI (R=0.601). At 6 weeks, 40.7% were functionally corrected, 39.4% were overcorrected, and 20.9% were under-corrected. The PJK incidence rate was 13.6%. Overcorrected patients had the highest PJK rate (18.1%) compared with functionally (11.3%) and under-corrected (9.5%) patients ( P <0.05). Overcorrected patients had a trend toward more PJK revisions. All groups improved in HRQL; however, under-corrected patients had the worst 1-year SF36-PCS offset relative to normative patients of equivalent age (−8.1) vs. functional (−6.1) and overcorrected (−4.5), P <0.05. Conclusions. T10PA was used to determine functional alignment, an alignment based on PI and age-appropriate physical function. Correcting patients to functional alignment produced improvements in clinical outcomes, with the lowest rates of PJK. This patient specific approach to spinal alignment provides ASD correction targets that can be used intraoperatively.