Details

Autor(en) / Beteiligte

• Huang, Jian-Ying
• Xia, Ling
• Xiao, Xiao-Hua
• Li, Gong-Ke

Titel

Advances in microchip electrophoresis for the separation and analysis of biological samples

Ist Teil von

• Se pu = Chinese journal of chromatography, 2023-08, Vol.41 (8), p.641

Ort / Verlag

China

Erscheinungsjahr

2023

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Microchip electrophoresis is a separation technology that involves fluid manipulation in a microchip; the advantages of this technique include high separation efficiency, low sample consumption, and fast and easy multistep integration. Microchip electrophoresis has been widely used to rapidly separate and analyze complex samples in biology and medicine. In this paper, we review the research progress on microchip electrophoresis, explore the fabrication and separation modes of microchip materials, and discuss their applications in the detection and analysis of biological samples. Research on microchip materials can be mainly categorized into chip materials, channel modifications, electrode materials, and electrode integration methods. Microchip materials research involves the development of silicon, glass, polydimethylsiloxane and polymethyl methacrylate-based, and paper electrophoretic materials. Microchannel modification research primarily focuses on the dynamic and static modification methods of microchanne