Details

Autor(en) / Beteiligte

• Jiang, Dong-Fang
• Zeng, Xing-Xing
• Li, De-Feng
• Wen, Si-Miaomiao
• Hu, Ming-Hua

Titel

Synthesis of α-allenic aldehydes/ketones from homopropargylic alcohols using a visible-light irradiation system

Ist Teil von

• Organic & biomolecular chemistry, 2023-06, Vol.21 (25), p.524-5244

Ort / Verlag

England: Royal Society of Chemistry

Erscheinungsjahr

2023

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A visible-light irradiation tandem oxidative aryl migration/carbonyl formation reaction, mediated by K 2 S 2 O 8 and visible-light photoredox catalysis, has been discovered. The presented transformation provides a straightforward access to important α-allenic aldehyde/ketone derivatives from readily available homopropargylic alcohol derivatives in a regioselective manner of 1,4-aryl shift concomitant with carbonyl formation. The operational simplicity and broad substrate scope demonstrate the great potential of this method for the synthesis of highly functional α-allenic aldehyde/ketone derivatives. A visible-light irradiation tandem oxidative aryl migration/carbonyl formation reaction, mediated by K 2 S 2 O 8 and visible-light photoredox catalysis, has been discovered.