Details

Autor(en) / Beteiligte

• Debillon, Louis
• Thorne, Jennifer E.
• Bousquet, Elodie
• Duraffour, Pierre
• Kecili, Souhila
• Monnet, Dominique
• Brézin, Antoine P.

Titel

Birdshot Chorioretinitis in Patients Aged 80 and Older

Ist Teil von

• Ocular immunology and inflammation, 2024-09, Vol.ahead-of-print (ahead-of-print), p.1-6

Ort / Verlag

England: Taylor & Francis

Erscheinungsjahr

2024

Quelle

MEDLINE

Beschreibungen/Notizen

• To assess the manifestations of birdshot chorioretinitis (BSCR) in patients aged 80 and over. Among patients with BSCR followed in the CO-BIRD prospective cohort (ClinicalTrials.gov Identifier: NCT05153057), we analyzed the subgroup of patients aged 80 and over. Patients were assessed in a standardized manner. Confluent atrophy was defined as hypoautofluorescent spots on fundus autofluorescence (FAF). We included 39 (8.8%) of the 442 enrolled CO-BIRD patients. The mean age was 83.8 ± 3.7 years. The mean logMAR BCVA was 0.52 ± 0.76, with 30 patients (76.9%) having 20/40 or better in at least one eye. Thirty-five (89.7%) patients were receiving no treatment. Confluent atrophy in the posterior pole, disrupted retrofoveal ellipsoid zone and choroidal neovascularization were associated with logMAR BCVA >0.3 (p < .0001). In patients aged 80 and over we observed a striking heterogeneity of outcomes, but most retained a BCVA that allowed them to drive.