Details

Autor(en) / Beteiligte

• She, Yu-Ping
• Zhang, Pei-Pei
• Hu, Jing-Yan
• Guo, Yong-Hua
• Cao, Qian
• Yin, Xiang
• Hu, Xiu-Hua
• Zhao, Ting
• Liu, Feng-Bo
• Zhang, Yuan
• Wei, Sheng-Li

Titel

Precise application of Beichaihu and Nanchaihu in classical formulas

Ist Teil von

• Zhongguo zhongyao zazhi, 2023-02, Vol.48 (3), p.681

Ort / Verlag

China

Erscheinungsjahr

2023

Quelle

MEDLINE

Beschreibungen/Notizen

• To maintain the precision and stability of the efficacy of classical formulas, this study compared the origins and specifications of Bupleuri Radix and revealed the precise application regularity of Bupleurum chinense(Beichaihu) and Bupleurum scorzonerifolium(Nanchaihu) in classical formulas. The efficacy and indications of formulas with Bupleuri Radix as the sovereign drug in the Treatise on Cold Damage and Miscellaneous Diseases(Shang Han Za Bing Lun) were investigated. The difference in the efficacy of Bupleuri Radix as well as the differences in the chemical composition, and liver-protecting and lipid-lowering effects of the decoctions of Beichaihu and Nanchaihu were analyzed with LC-MS technology based on the CCl_4-induced liver injury model in mice and sodium oleate-induced HepG2 hyperlipidemia cell model. The results showed that seven classical formulas with Bupleuri Radix as the sovereign drug in the Treatise on Cold Damage and Miscellaneous Diseases were mainly used in the treatment of digestive, met