Details

Autor(en) / Beteiligte

• Lawal, Ismaheel O
• Adediran, Omotayo Atinuke
• Muzahir, Saima
• Friend, Sarah
• Bhave, Manali Ajay
• Meisel, Jane
• Torres, Mylin A
• Styblo, Toncred Marya
• Graham, Cathy
• Holbrook, Anna
• Kalinsky, Kevin
• Fielder, Bridget
• Crowe, Ronald J
• Ulaner, Gary A
• Schuster, David M

Titel

A Tale of 3 Tracers: Contrasting Uptake Patterns of 18F-Fluciclovine, 68Ga-PSMA, and 18F-FDG in the Uterus and Adnexa

Ist Teil von

• Clinical nuclear medicine, 2023-01, Vol.48 (1), p.e26-e27

Ort / Verlag

United States

Erscheinungsjahr

2023

Quelle

MEDLINE

Beschreibungen/Notizen

• A 41-year-old woman with invasive lobular carcinoma of the breast underwent sequential 68Ga-PSMA-11 PET/CT and 18F-fluciclovine PET/CT as part of an ongoing clinical trial (NCT04750473). 68Ga-PSMA PET/CT showed increased radiotracer uptake in the uterine endometrium and left adnexa. 18F-fluciclovine PET/CT showed increased radiotracer uptake in a leiomyomatous uterus. A clinical 18F-FDG PET/CT demonstrated radiotracer uptake in the endometrium and a circumferential area of uptake in the left adnexa, a pattern more similar to the 68Ga-PSMA uptake pattern. This case highlights the discordance in the uptake pattern of 2 radiotracers approved for prostate cancer imaging but increasingly used in non-prostate malignancies imaging.