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Research advances on the construction of an ideal scar model in vitro based on innovative tissue engineering technology
Ist Teil von
Zhonghua shao shang yu chuang mian xiu fu za zhi, 2022-10, Vol.38 (10), p.983
Ort / Verlag
China
Erscheinungsjahr
2022
Quelle
MEDLINE
Beschreibungen/Notizen
The scar brings a huge economic burden and creates a serious psychological shadow for patients. Although the current methods for scar treatment tend to be diversified, the treatment method that can truly achieve the goal of "perfect healing" or "scarless healing" after human skin injury is quite scarce. With the wide application of tissue engineering technologies in medicine research, technologies such as three-dimensional bioprinting, organoid culture, and organ chip technologies are constantly emerging. Disease models
based on these innovative technologies showed more advantages than traditional animal disease models. The article introduces the current hotspot technologies in skin tissue engineering such as organoid culture, three-dimensional bioprinting, and organ chip technologies, focuses on summarizing the three key elements to be mastered for constructing an ideal scar model
, and puts forward the future prospect of constructing an ideal scar model
based on our research team's long-term experience in s