Details

Autor(en) / Beteiligte

• DiPietro, J A
• Lock, T F
• Todd, Jr, K S
• Reuter, V E

Titel

Evaluation of ivermectin paste in the treatment of ponies for Parascaris equorum infections

Ist Teil von

• Journal of the American Veterinary Medical Association, 1987-05, Vol.190 (9), p.1181

Ort / Verlag

United States

Erscheinungsjahr

1987

Quelle

MEDLINE

Beschreibungen/Notizen

• Twenty ponies less than 18 months of age and infected with Parascaris equorum were treated with either 0.2 mg of ivermectin/kg of body weight (n = 10) or a placebo (n = 10; controls). Five control and 5 ivermectin-treated ponies were euthanatized 14 and 35 days after treatment, respectively. At necropsy, the small intestinal contents, lungs, and liver were examined for larvae and/or adult P equorum. Significantly (P less than 0.02) higher mean total numbers of P equorum were found in the small intestinal contents of the controls on day 14 (51) and on day 35 (21) than in the ivermectin-treated ponies on days 14 (0) and 35 (3). The efficacy of ivermectin in removing adult and intestinal larvae of P equorum at 14 days after treatment was 100%. The efficacies of ivermectin in removing adults and intestinal larvae of P equorum at 35 days after treatment were 100% and 76.9%, respectively. Gross examination of liver and lung tissues revealed damage as a result of P equorum infections in all ponies. The Baermann technique used on liver and lung tissues did not yield any P equorum larvae. Adverse reactions attributable to treatment were not observed.