Details

Autor(en) / Beteiligte

• Ishiguro, Toru
• Mochiki, Erito
• Ito, Tetsuya
• Ishikawa, Hiroyasu
• Yamamoto, Eisuke
• Sato, Taku
• Chikatani, Kenichi
• Yamamoto, Azusa
• Chika, Noriyasu
• Toyomasu, Yoshitaka
• Hatano, Satoshi
• Kumagai, Yoichi
• Ishibashi, Keiichiro
• Maki, Akira
• Ishida, Hideyuki

Titel

Conversion Surgery following Second-Line Chemotherapy for Unresectable Gastric Cancer

Ist Teil von

• Gan to kagaku ryoho, 2021-12, Vol.48 (13), p.1828

Ort / Verlag

Japan

Erscheinungsjahr

2021

Quelle

MEDLINE

Beschreibungen/Notizen

• We retrospectively analyzed clinicopathological and survival data of 8 patients with unresectable gastric cancer who underwent conversion surgery(CS)following second-line chemotherapy from April 2013 to December 2020. There were 7 males and 1 female patients with a median age of 69(64-76)years old. Five patients had 1 unresectable factor, 2 had 2 unresectable factors, and 1 had 3 unresectable factors. All patients achieved R0 resection. The median survival time(MST) of patients with CS following second-line chemotherapy was significantly longer than that without CS(73.4 vs 12.3 months, respectively). The MST of patients with CS following first-line chemotherapy was significantly longer than that without CS (22.9 vs 12.3 months, respectively). This study suggested that CS following first- or second-line chemotherapy may improve survival duration for unresectable gastric cancer.