Details

Autor(en) / Beteiligte

• Mugetti, Davide
• Colombino, Elena
• Capucchio, Maria Teresa
• Salogni, Christian
• Pastorino, Paolo
• Chiappino, Laura
• Sereno, Alessandra
• Prearo, Marino
• Guarda, Franco

Titel

Teleost fish: a new spontaneous model for the study of Lambl's excrescences

Ist Teil von

• Diseases of aquatic organisms, 2021-10, Vol.146, p.75-79

Ort / Verlag

Germany

Erscheinungsjahr

2021

Quelle

MEDLINE

Beschreibungen/Notizen

• Lambl's excrescences (LE) are fibrous strands typically occurring at coaptation lines of cardiac valves. Although they have been widely reported in human medicine, information on LE occurrence in veterinary medicine is still scarce. The present study aimed to investigate the presence of LE in different freshwater fish and in swordfish. A total of 185 hearts were collected from different fish species, and samples of different cardiac areas (sinus venosus, atrial wall with sinoatrial valves, ventricular wall with atrioventricular valves and bulb with bulboventricular valves) were submitted to histopathological evaluation. LE were detected in 6 of 103 freshwater fish (5.8%) and 19 of 82 swordfish (23.2%). LE developed in atrioventricular, sinoatrial and bulboventricular valves. All affected valves also showed endocardiosis. Based on the results of the present work, teleost fish, specifically swordfish, could be proposed as a novel spontaneous model for the study of LE pathogenesis.