Details

Autor(en) / Beteiligte

• Vlaicu, R
• Rus, H G
• Niculescu, F

Titel

Immunohistochemical localization of the terminal C5b-9 complement complexes associated to S-protein and macrophage immunoreactive deposits in human damaged myocardial areas

Ist Teil von

• Medecine interne, 1988-01, Vol.26 (1), p.21

Ort / Verlag

Romania

Erscheinungsjahr

1988

Quelle

MEDLINE

Beschreibungen/Notizen

• The indirect and double-labelling immunoperoxidase techniques were used to localize the C5b-9 neoantigens, S-protein and macrophage immunoreactive deposits in myocardial areas with necrosis and sclerosis. Granular masses of C5b-9 neoantigens, diffuse areas of S-protein and nucleated and anucleated immunoreactive deposits of macrophage origin were localized in damaged myocardial areas but not in areas free of lesion. The presence of C5b-9 neoantigens associated to S-protein and macrophage deposits is suggestive for a local complement activation in the complex heterolytic events of myocardial injury.