Details

Autor(en) / Beteiligte

• Wang, J F
• Fang, C
• Yang, G
• Lu, J
• Zhang, S T
• Li, L L
• Liu, H M
• Xu, M E
• Ren, X F
• Ma, L J
• Yu, H
• Wei, G
• Hou, J B
• Yang, S
• Dai, J N
• Yu, B

Titel

Impact of inflammatory reaction levels and culprit plaque characteristics on preprocedural thrombolysis in myocardial infarction flow grade in patients with ST-segment elevation myocardial infarction

Ist Teil von

• Zhōnghuá xīnxuèguănbìng zázhì, 2021-02, Vol.49 (2), p.150

Ort / Verlag

China

Erscheinungsjahr

2021

Quelle

MEDLINE

Beschreibungen/Notizen

• To determine the impact of inflammatory reaction levels and the culprit plaque characteristics on preprocedural Thrombolysis in Myocardial Infarction (TIMI) flow grade in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). The is a retrospective study. A total of 1 268 STEMI patients who underwent pre-intervention optical coherence tomography (OCT) examination of culprit lesion during emergency PCI were divided into 2 groups by preprocedural TIMI flow grade (TIMI 0-1 group ( =964, 76.0%) and TIMI 2-3 group ( =304, 24.0%)). Baseline clinical data of the 2 groups were collected; blood samples were collected for the detection of inflammatory markers such as high sensitivity C-reactive protein (hsCRP), myocardial injury marker, blood lipid, etc.; echocardiography was used to determine left ventricular ejection fraction; coronary angiography and OCT were performed to define the lesion length, diameter stenosis degree of the infarct-related ar