Details

Autor(en) / Beteiligte

• Hatano, Satoshi
• Yamamoto, Eisuke
• Toyomasu, Yoshitaka
• Ishiguro, Toru
• Kumagai, Yoichi
• Ishibashi, Keiichiro
• Mochiki, Erito
• Ishida, Hideyuki
• Suzuki, Shinichi

Titel

A Case of Papillary Carcinoma of Thyroid Associated with Familial Adenomatous Polyposis in a Younger Woman

Ist Teil von

• Gan to kagaku ryoho, 2021-02, Vol.48 (2), p.236

Ort / Verlag

Japan

Erscheinungsjahr

2021

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Familial adenomatous polyposis(FAP)is an autosomal dominantly inherited disorder, and the result of a germ line variant in the adenomatous poplyposis coli(APC)gene. FAP can be associated with various extracolonic lesions including thyroid cancer, which frequently occurs in women. We report the case of a 15-year-old woman diagnosed as FAP with multiple thyroid papillary carcinomas. Her mother had been treated for FAP with colorectal cancer and thyroid cancer in our department. Multiple tumors with a maximum diameter of 17 mm were detected in the right lobe of the thyroid gland during the preoperative examination. Papillary carcinoma was suspected based on fine-needle aspiration cytology. She was diagnosed with FAP because of multiple polyps on colonoscopy. We performed a subtotal thyroidectomy. Pathological findings revealed a cribriform-morular variant of papillary thyroid carcinoma. We report a rare case of papillary carcinoma of thyroid associated with FAP in a younger woman.